PW01-009 – Markers of inflammation in adult FMF patients
نویسندگان
چکیده
Methods 40 consecutive patients suffering from FMF according to the Livneh criteria and 40 healthy controls (C) were included into the study in Herne, Germany. All participants were Turkish migrants aged ≥18 years. Patients were excluded if they reported symptoms of FMF ≤7 days prior to inclusion. Frequency of FMF attacks during the 3 months preceding the study inclusion was assessed. Patients were grouped into patients without (F-) or with (F+) attacks. The following markers were determined: erythrocyte sedimentation rate (ESR, ref: <20mm/h), C-reactive protein (CRP, ref: <0.5mg/dl), serum amyloid A (SAA, ref: <0.5mg/dl), fibrinogen (FI, ref: 2.38-4.98 g/l) and S100A12 (ref: <120 ng/ml).
منابع مشابه
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Introduction MEFV is the first identified autoinflammatory gene related to Familial Mediterranean Fever (FMF) disease. We previously the tested the hypothesize of epigenetic involvement in FMF, mainly based on the occurrence of FMF in patients without mutations and decreased MEFV transcripts in leukocyte samples independent from mutations. Our study showed that higher methylation level of MEFV ...
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عنوان ژورنال:
دوره 11 شماره
صفحات -
تاریخ انتشار 2013